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MedChemExpress
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Shanghai Macklin Biochemical
potassium oxonate ![]() Potassium Oxonate, supplied by Shanghai Macklin Biochemical, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/oxon/pmc13149162-73-6-13?v=Shanghai+Macklin+Biochemical Average 86 stars, based on 1 article reviews
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Macklin Inc
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Merck & Co
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Thermo Fisher
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Macklin Inc
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Routledge Ltd
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Journal: Frontiers in Immunology
Article Title: Baicalein links macrophage M2 polarization with reduced synovial inflammation to alleviate gouty arthritis
doi: 10.3389/fimmu.2026.1812532
Figure Lengend Snippet: Schematic diagram of the experimental protocol for establishing a hyperuricemia-induced acute gouty arthritis mouse model and baicalein intervention. Male Balb/c mice were administered Potassium Oxonate (PO) and Yeast Extract via oral gavage from Day 1 to Day 35. Acute gouty arthritis was induced by intra-articular injection of monosodium urate (MSU) crystals into the left ankle joint from Day 29 to Day 35 . Starting from Day 29, all groups received daily oral gavage treatments (including baicalein and saline control). Relevant signs in mice, including body weight, food intake, water intake, urine output, ankle swelling, and gait, were monitored regularly. On Day 35, mice were euthanized, and serum, liver, kidney, and ankle joint tissues were collected for subsequent biochemical, histopathological, and molecular biological analyses. This protocol allows for a comprehensive evaluation of the anti-inflammatory and uricosuric effects of baicalein in a clinically relevant gout model.
Article Snippet: Key reagents for inducing hyperuricemia included
Techniques: Injection, Saline, Control